Ĭopernicus was born and died in Royal Prussia, a region that had been part of the Kingdom of Poland since 1466. The publication of Copernicus's model in his book De revolutionibus orbium coelestium ( On the Revolutions of the Celestial Spheres), just before his death in 1543, was a major event in the history of science, triggering the Copernican Revolution and making a pioneering contribution to the Scientific Revolution. In all likelihood, Copernicus developed his model independently of Aristarchus of Samos, an ancient Greek astronomer who had formulated such a model some eighteen centuries earlier. Inhibitory effect of an ellagic acid-rich pomegranate extract on tyrosinase activity and ultraviolet-induced pigmentation.Nicolaus Copernicus (19 February 1473 – ) was a Renaissance polymath, active as a mathematician, astronomer, and Catholic canon, who formulated a model of the universe that placed the Sun rather than Earth at its center. Nobiletin as a tyrosinase inhibitor from the peel of citrus fruit. Modulation of antioxidant defense by Alpinia galangal and Curcuma aromatica extracts correlates with their inhibition of UVA-induced melanogenesis. Aloesin and arbutin inhibit tyrosinase activity in a synergistic manner via a different action mechanism. An updated review of tyrosinase inhibitors. You can learn more about how we ensure our content is accurate and current by reading our editorial policy. Healthline has strict sourcing guidelines and relies on peer-reviewed studies, academic research institutions, and medical associations. Once your lips are clean and dry, apply a thin layer of petroleum jelly. Leave in place for 5 to 10 minutes, then rinse off. Twice a week, apply the beet paste to your lips. Using a food processor or blender, grind beetroot into a fine paste. Once per day, gently massage one to two drops of mustard oil on your lips. If you like, you can substitute olive oil for the butter. Three times a week, massage this blend onto your lips for three to four minutes. Blend together 3 teaspoons of sugar and 2 teaspoons of butter. Every night before bed, massage a drop or two of almond oil onto your lips. Massage the paste onto your lips for three to five minutes. In a small bowl, blend 1 tablespoon of fresh dairy cream and enough almond powder to make a paste. Gently apply this paste to your lips at bedtime, then rinse off with cool water the next morning. Make a paste by mixing together five crushed, medium-sized strawberries and 2 teaspoons of baking soda. Leave the cucumber juice on your lips for about 30 minutes, then rinse off with cool water. Once the juice is cool, dip a cotton ball into it and use the cotton ball to gently apply the juice onto your lips. Before bed, massage a few drops of olive oil onto your lips. You can also apply this mixture before going to bed at night. Apply this mixture to your lips three to four times per day. Mix together two drops of rose water to six drops of honey. You can do this multiple times during the day and also before you go to sleep at night. Using your fingertip, take a very small amount of coconut oil and gently apply it evenly over your lips. However, research is needed to explore their effectiveness. Some people use the following home remedies to lighten darker lips. Gently massage the paste into your lips for about three minutes, then rinse your lips with cool water. To make this remedy, mix the following into a paste: PomegranateĪ 2005 study found that pomegranate extract may lighten skin hyperpigmentation. Once it’s dried, rinse it off with warm water. Once each day, apply a thin layer of fresh aloe vera gel onto your lips. AloeĪn older study suggests a compound in aloe vera inhibits melanin production. After drying your lips, apply your favorite moisturizer. Leave it in place for about five minutes before gently rinsing it off with cool water. With a wet fingertip, rub the paste on your lips. TurmericĪccording to a 2010 study, turmeric may act as a melanin inhibitor. Gently apply the mixture to your lips before bedtime. Lime is another citrus fruit that may have anti-melanin production properties. The next morning, rinse your lips with lukewarm water. Lemon and sugarīefore bedtime, cut a lemon wedge and dip it in sugar. Repeat this routine every night until you see results. The next morning, rinse your lips with cool water. Every night just before going to sleep, cut a lemon and gently rub the juicy part over your lips. LemonĪ 2002 study suggests citrus fruit peel may act as a melanin inhibitor. You might, however, find a natural lip lightener that suits your needs. Many hyperpigmentation treatments work by inhibiting an enzyme that produces melanin. Laser treatments and chemicals such as hydroquinone and kojic acid are often used to treat lip hyperpigmentation. Treating hyperpigmentation is often a cosmetic decision.
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